Pengfei Zhang

SUMOylation inhibitors synergize with FXR agonists in combating liver fibrosis

Jiyu Zhou, Shuang Cui, Qingxian He et al. · Nature Communications · 2020 · 137 citations · Full text

Discovery of novel hybrids of diaryl-1,2,4-triazoles and caffeic acid as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase for cancer therapy

Hao Cai, Xiaojing Huang, Shengtao Xu et al. · European Journal of Medicinal Chemistry · 2015 · 99 citations · Full text

Medicinal Chemistry, Dual Inhibitors, Medicine +9

Dietary intake of fructose increases purine de novo synthesis: A crucial mechanism for hyperuricemia

Pengfei Zhang, Huimin Sun, Xinyu Cheng et al. · Frontiers in Nutrition · 2022 · 46 citations · Full text

Discovery of novel antitumor nitric oxide-donating β -elemene hybrids through inhibiting the PI3K/Akt pathway

Jichao Chen, Tianyu Wang, Shengtao Xu et al. · European Journal of Medicinal Chemistry · 2017 · 45 citations · Full text

Medicinal Chemistry, Drug Targeting, Medicine +7

SIRT1 activation synergizes with FXR agonism in hepatoprotection via governing nucleocytoplasmic shuttling and degradation of FXR

Shuang Cui, Huijian Hu, An Chen et al. · Acta Pharmaceutica Sinica B · 2022 · 27 citations · Full text