Chen Chen

Selenomethionine Mitigates Cognitive Decline by Targeting Both Tau Hyperphosphorylation and Autophagic Clearance in an Alzheimer's Disease Mouse Model

Zhong-Hao Zhang, Qiuyan Wu, Rui Zheng et al. · Journal of Neuroscience · 2017 · 122 citations · Full text

Selenomethionine Ameliorates Cognitive Decline, Reduces Tau Hyperphosphorylation, and Reverses Synaptic Deficit in the Triple Transgenic Mouse Model of Alzheimer's Disease

Guo-Li Song, Zhong-Hao Zhang, Lei Wen et al. · Journal of Alzheimer s Disease · 2014 · 84 citations

Selenomethionine promoted hippocampal neurogenesis via the PI3K-Akt-GSK3β-Wnt pathway in a mouse model of Alzheimer's disease

Rui Zheng, Zhong-Hao Zhang, Chen Chen et al. · Biochemical and Biophysical Research Communications · 2017 · 74 citations

Neurodegenerative Diseases, Synaptic Plasticity, Alzheimer's Disease +14

Selenoprotein K deficiency-induced apoptosis: A role for calpain and the ERS pathway

Shi-Zheng Jia, Xin-Wen Xu, Zhong-Hao Zhang et al. · Redox Biology · 2021 · 69 citations · Full text

Long-Term Dietary Supplementation with Selenium-Enriched Yeast Improves Cognitive Impairment, Reverses Synaptic Deficits, and Mitigates Tau Pathology in a Triple Transgenic Mouse Model of Alzheimer’s Disease

Zhong-Hao Zhang, Lei Wen, Qiuyan Wu et al. · Journal of Agricultural and Food Chemistry · 2017 · 46 citations

Neurochemical Biomarkers, Mitigates Tau Pathology, Social Sciences +21