The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation by promoting proteasomal degradation of NLRP3

Hui Song, Bingyu Liu, Wanwan Huai, +8

Nature Communications

Chronic Inflammatory DiseasesTrim31 DeficiencyImmunologyImmune RegulationCell Death +19

Redox homeostasis maintained by GPX4 facilitates STING activation

Mutian Jia, Danhui Qin, Chunyuan Zhao, +9

Nature Immunology

InflammationSignal TransductionRedox RegulatorPhysiologyRedox Biology +5

USP1–UAF1 deubiquitinase complex stabilizes TBK1 and enhances antiviral responses

Zhongxia Yu, Hui Song, Mutian Jia, +5

The Journal of Experimental Medicine

lncRNA Ftx promotes aerobic glycolysis and tumor progression through the PPARγ pathway in hepatocellular carcinoma

Xiao Li, Qi Zhao, Jianni Qi, +4

International Journal of Oncology

Metabolic RemodelingTumor BiologyOxidative StressPparγ PathwayCancer Cell Biology +22

RNF39 mediates K48-linked ubiquitination of DDX3X and inhibits RLR-dependent antiviral immunity

Wenwen Wang, Mutian Jia, Chunyuan Zhao, +4

Science Advances

Autophagy plays an important role in triptolide-induced apoptosis in cardiomyocytes

Jie Zhou, Xi Chen, Wenwen Wang, +3

Toxicology Letters

Cell AutophagyMitophagyHeart FailureSignal TransductionCardiomyopathy +11

MAPK/p38 regulation of cytoskeleton rearrangement accelerates induction of macrophage activation by TLR4, but not TLR3

Hongjun Bian, Feifei Li, Wenwen Wang, +7

International Journal of Molecular Medicine

Macrophage ActivationInnate Immune SystemImmunologyImmune RegulationImmunologic Mechanism +25

Abortive Infection of Snakehead Fish Vesiculovirus in ZF4 Cells Was Associated with the RLRs Pathway Activation by Viral Replicative Intermediates

Wenwen Wang, Muhammad Asim, Lizhu Yi, +5

International Journal of Molecular Sciences

Viral ReplicationViral PathogenesisImmunologyViral Replicative IntermediatesViral Mrnas +14

Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation

Wenwen Wang, Ying Qin, Hui Song, +5

The Journal of Immunology

Mint3 potentiates TLR3/4- and RIG-I–induced IFN-β expression and antiviral immune responses

Wanwan Huai, Hui Song, Zhongxia Yu, +7

Proceedings of the National Academy of Sciences