Fan Zhang

Nuclear cGAS suppresses DNA repair and promotes tumorigenesis

Haipeng Liu, Haiping Zhang, Xiangyang Wu et al. · Nature · 2018 · 617 citations

Chromatin, Genome Instability, Chromatin Remodeling +5

Oncogenic PIK3CA-driven mammary tumors frequently recur via PI3K pathway–dependent and PI3K pathway–independent mechanisms

Pixu Liu, Hailing Cheng, Stephanie Santiago et al. · Nature Medicine · 2011 · 259 citations · Full text

Oncology, Pi3k Pathway–independent Mechanisms, Medicine +9

Structural Insights into the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschii

Fan Zhang, Min Hu, Geng Tian et al. · Molecular Cell · 2009 · 165 citations · Full text

Biosynthesis, Prokaryotic System, Biochemistry +13

SCML2 Establishes the Male Germline Epigenome through Regulation of Histone H2A Ubiquitination

Kazuteru Hasegawa, Ho-Su Sin, So Maezawa et al. · Developmental Cell · 2015 · 150 citations · Full text

Histone Modifications, Chromatin, Male Germline Epigenome +15

RNF8 regulates active epigenetic modifications and escape gene activation from inactive sex chromosomes in post-meiotic spermatids

Ho-Su Sin, Artem Barski, Fan Zhang et al. · Genes & Development · 2012 · 148 citations · Full text

Histone Modifications, Spermatogenesis, Epigenetic Change +21