Jian Wang

Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy

Peter S. Dragovich, Thomas H. Pillow, Robert A. Blake et al. · Journal of Medicinal Chemistry · 2021 · 169 citations

Pharmacy, Biochemistry, Medicinal Chemistry +17

Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 1: Exploration of Antibody Linker, Payload Loading, and Payload Molecular Properties

Peter S. Dragovich, Thomas H. Pillow, Robert A. Blake et al. · Journal of Medicinal Chemistry · 2021 · 150 citations

Pharmacy, Oncology, Pharmacology +17

Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains

Terry D. Crawford, Vickie Tsui, E. Megan Flynn et al. · Journal of Medicinal Chemistry · 2016 · 118 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637)

Alexander M. Taylor, Alexandre Côté, Michael C. Hewitt et al. · ACS Medicinal Chemistry Letters · 2016 · 112 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

CNT/Sericin Conductive Nerve Guidance Conduit Promotes Functional Recovery of Transected Peripheral Nerve Injury in a Rat Model

Xiaolin Li, Wen Yang, Hongjian Xie et al. · ACS Applied Materials & Interfaces · 2020 · 112 citations

Engineering, Bioengineering, Biomedical Engineering +17