Wenbo Chen

Development of a quantitative relationship between CAR-affinity, antigen abundance, tumor cell depletion and CAR-T cell expansion using a multiscale systems PK-PD model

Aman P. Singh, Xirong Zheng, Xiefan Lin‐Schmidt et al. · mAbs · 2019 · 113 citations · Full text

Medicine, Oncology, Pharmacology +17

Transcription factor <i>Dmrt1</i> triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility

Meng-Fei Zhang, Shicheng Wan, Wenbo Chen et al. · 动物学研究 · 2023 · 42 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Design, synthesis and biological evaluation of paralleled Aza resveratrol–chalcone compounds as potential anti-inflammatory agents for the treatment of acute lung injury

Wenbo Chen, Xiangting Ge, Fengli Xu et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 32 citations

Medicine, Medicinal Chemistry, Pharmacology +14

A physiological model of granulopoiesis to predict clinical drug induced neutropenia from in vitro bone marrow studies: with application to a cell cycle inhibitor

Wenbo Chen, Britton Boras, Tae Sung et al. · Journal of Pharmacokinetics and Pharmacodynamics · 2020 · 14 citations · Full text

Medicine, Cell Biology, Hematology +16

UCP2 overexpression activates SIRT3 to regulate oxidative stress and mitochondrial dynamics induced by myocardial injury

Zhengguang Geng, Wenbo Chen, Qinju Lu et al. · Archives of Biochemistry and Biophysics · 2024 · 14 citations

Life Sciences, Biochemistry, Molecular Biology +17