Hao Chen

Comprehensive analysis of prognostic immune‐related genes in the tumor microenvironment of cutaneous melanoma

Sheng Yang, Tong Liu, Hongmei Nan et al. · Journal of Cellular Physiology · 2019 · 110 citations

Design, synthesis, evaluation, and SAR of 4-phenylindoline derivatives, a novel class of small-molecule inhibitors of the programmed cell death-1/ programmed cell death-ligand 1 (PD-1/PD-L1) interaction

Yang Yang, Ke Wang, Hao Chen et al. · European Journal of Medicinal Chemistry · 2020 · 38 citations · Full text

Medicinal Chemistry, Biochemistry, Natural Sciences +11

Targeted delivery of a PD-1-blocking scFv by CD133-specific CAR-T cells using nonviral Sleeping Beauty transposition shows enhanced antitumour efficacy for advanced hepatocellular carcinoma

Chaopin Yang, Jinqi You, Qiuzhong Pan et al. · BMC Medicine · 2023 · 34 citations · Full text

Delineating Novel Metabolic Pathways of DPC 963, a Non-Nucleoside Reverse Transcriptase Inhibitor, in Rats. Characterization of Glutathione Conjugates of Postulated Oxirene and Benzoquinone Imine Intermediates by LC/MS and LC/NMR

Hao Chen, John P. Shockcor, Weiqi Chen et al. · Chemical Research in Toxicology · 2002 · 28 citations

Metabolomic Profiling, Benzoquinone Imine Intermediates, Oxidative Stress +17

Design, synthesis, and biological evaluation of 1-methyl-1H-pyrazolo[4,3-b]pyridine derivatives as novel small-molecule inhibitors targeting the PD-1/PD-L1 interaction

Xinyan Dai, Ke Wang, Hao Chen et al. · Bioorganic Chemistry · 2021 · 26 citations

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +11