CP-25, a novel compound, protects against autoimmune arthritis by modulating immune mediators of inflammation and bone damage

Yan Chang, Xiaoyi Jia, Wei Fang, +9

Scientific Reports

Ginsenoside Metabolite Compound K Alleviates Adjuvant-Induced Arthritis by Suppressing T Cell Activation

Jingyu Chen, Huaxun Wu, Qingtong Wang, +12

Inflammation

InflammationRheumatologyT Cell ActivationCytokineAnti-inflammatory +9

Ginsenoside metabolite compound K exerts anti-inflammatory and analgesic effects via downregulating COX2

Jingyu Chen, Min Si, Ying Wang, +4

Inflammopharmacology

InflammationAnti-inflammatoryPain MedicineMedicineChronic Inflammation +7

A Modified Compound From Paeoniflorin, CP-25, Suppressed Immune Responses and Synovium Inflammation in Collagen-Induced Arthritis Mice

Jingyu Chen, Ying Wang, Huaxun Wu, +3

Frontiers in Pharmacology

Ginsenoside Metabolite Compound K Suppresses T-Cell Priming via Modulation of Dendritic Cell Trafficking and Costimulatory Signals, Resulting in Alleviation of Collagen-Induced Arthritis

Jingyu Chen, Huaxun Wu, Qingtong Wang, +3

Journal of Pharmacology and Experimental Therapeutics

GRK2 Mediated Abnormal Transduction of PGE2-EP4-cAMP-CREB Signaling Induces the Imbalance of Macrophages Polarization in Collagen-Induced Arthritis Mice

Xuezhi Yang, Susu Li, Yingjie Zhao, +12

Cells

Pro-apoptotic effect of Epigallo-catechin-3-gallate on B lymphocytes through regulating BAFF/PI3K/Akt/mTOR signaling in rats with collagen-induced arthritis

Dandan Liu, Peipei Li, Shanshan Song, +8

European Journal of Pharmacology

InflammationRheumatologyRheumatoid DisorderAnti-inflammatoryAutoimmune Disease +11

Ginsenoside metabolite compound K attenuates inflammatory responses of adjuvant-induced arthritis rats

Huaxun Wu, Jingyu Chen, Qingtong Wang, +8

Immunopharmacology and Immunotoxicology

Deficiency of β-arrestin2 exacerbates inflammatory arthritis by facilitating plasma cell formation

Weijie Zhou, Dandan Wang, Juan Tao, +11

Acta Pharmacologica Sinica

InflammationRheumatologyCytokineInflammatory DiseaseAutoimmune Disease +10

Involvement of the prostaglandin E receptor EP2 in paeoniflorin-induced human hepatoma cell apoptosis

Shanshan Hu, Wu‐Yi Sun, Wei Wei, +6

Anti-Cancer Drugs

Chemoprevention StrategyApoptosisImmunologyCell DeathEp2 Expression +15