Dendritic cells with an increased PD-L1 by TGF-β induce T cell anergy for the cytotoxicity of hepatocellular carcinoma cells

Shasha Song, Pingfan Yuan, Huaxun Wu, +5

International Immunopharmacology

Cancer ImmunosurveillanceAllergyImmunologyTumor ImmunityHepatocellular Carcinoma Cells +7

Therapeutic effects of TACI-Ig on rats with adjuvant-induced arthritis via attenuating inflammatory responses

Yan Chang, Yujing Wu, Di Wang, +12

Lara D. Veeken

CP-25, a novel compound, protects against autoimmune arthritis by modulating immune mediators of inflammation and bone damage

Yan Chang, Xiaoyi Jia, Wei Fang, +9

Scientific Reports

Role of p38γ MAPK in regulation of EMT and cancer stem cells

Mei Xu, Siying Wang, Yongchao Wang, +4

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Cancer ResearchSignaling PathwayHealth SciencesCell RegulationMedicine +9

Ginsenoside Metabolite Compound K Alleviates Adjuvant-Induced Arthritis by Suppressing T Cell Activation

Jingyu Chen, Huaxun Wu, Qingtong Wang, +12

Inflammation

InflammationRheumatologyT Cell ActivationCytokineAnti-inflammatory +9

β2-adrenoceptor signaling reduction in dendritic cells is involved in the inflammatory response in adjuvant-induced arthritic rats

Huaxun Wu, Jingyu Chen, Shasha Song, +7

Scientific Reports

JAK1-STAT3 blockade by JAK inhibitor SHR0302 attenuates inflammatory responses of adjuvant-induced arthritis rats and decreases Th17 and total B cells

Huaxun Wu, Shangxue Yan, Jingyu Chen, +12

Joint Bone Spine

InflammationRheumatologyInflammatory ResponsesCytokineRheumatoid Disorder +13

Total glucosides of paeony inhibit the proliferation of fibroblast-like synoviocytes through the regulation of G proteins in rats with collagen-induced arthritis

Xiaoyi Jia, Yan Chang, Xiaojing Sun, +8

International Immunopharmacology

InflammationRheumatologyRheumatoid DisorderAnti-inflammatoryAutoimmune Disease +12

CP-25 reverses prostaglandin E4 receptor desensitization-induced fibroblast-like synoviocyte dysfunction via the G protein-coupled receptor kinase 2 in autoimmune arthritis

Xiaoyi Jia, Yan Chang, Wei Fang, +8

Acta Pharmacologica Sinica

InflammationRheumatologyRheumatoid DisorderAutoimmune DiseaseG Protein-coupled Receptor +10

A Modified Compound From Paeoniflorin, CP-25, Suppressed Immune Responses and Synovium Inflammation in Collagen-Induced Arthritis Mice

Jingyu Chen, Ying Wang, Huaxun Wu, +3

Frontiers in Pharmacology