Updated Trends in Hematopoietic Cell Transplantation in the United States with an Additional Focus on Adolescent and Young Adult Transplantation Activity and Outcomes

Rachel Phelan, Min Chen, Caitrin Bupp, +28

Transplantation and Cellular Therapy

Targeting Primitive Chronic Myeloid Leukemia Cells by Effective Inhibition of a New AHI-1–BCR-ABL–JAK2 Complex

Min Chen, Paolo Gallipoli, Donna DeGeer, +19

JNCI Journal of the National Cancer Institute

Haematopoietic stem cells depend on Gαs-mediated signalling to engraft bone marrow

Gregor B. Adams, Ian R. Alley, Ung-il Chung, +9

Nature

Developmental BiologyMarrow TransplantationHaematopoietic Stem CellsMedicineStem Cell Transplantation +10

The miR-185/PAK6 axis predicts therapy response and regulates survival of drug-resistant leukemic stem cells in CML

Hanyang Lin, Katharina Rothe, Min Chen, +17

Blood

PP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL ⁺ human leukemia

Damian Lai, Min Chen, Jiechuang Su, +7

Science Translational Medicine

Integrin-Linked Kinase Mediates Therapeutic Resistance of Quiescent CML Stem Cells to Tyrosine Kinase Inhibitors

Katharina Rothe, Artem Babaian, Naoto Nakamichi, +8

Cell stem cell

MedicineReceptor Tyrosine KinaseAdult Stem CellKinase InhibitorsCell-matrix Interaction +6

Targeting AXL kinase sensitizes leukemic stem and progenitor cells to venetoclax treatment in acute myeloid leukemia

Xiaojia Niu, Katharina Rothe, Min Chen, +20

Blood

Selective JAK2/ABL dual inhibition therapy effectively eliminates TKI-insensitive CML stem/progenitor cells

Hanyang Lin, Min Chen, Katharina Rothe, +3

Oncotarget

PP2A is a therapeutically targetable driver of cell fate decisions via a c-Myc/p21 axis in human and murine acute myeloid leukemia

Swagata Goswami, Rajeswaran Mani, Jessica Nunes, +26

Blood

Targetable DriverHematological MalignancyC-myc/p21 AxisCell SignalingAcute Myeloid Leukemia +13

siRNA-mediated BCR-ABL silencing in primary chronic myeloid leukemia cells using lipopolymers

Juliana Valencia‐Serna, Cezary Kucharski, Min Chen, +3

Journal of Controlled Release

Hematological MalignancyTumor BiologyOncologyMedicineSirna-mediated Bcr-abl Silencing +4