Long Chen

Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5

Long Chen, Lei Liu, Shile Huang · Free Radical Biology and Medicine · 2008 · 262 citations

Signal Transduction, Biochemistry, Medicine +9

Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death

Long Chen, Baoshan Xu, Lei Liu et al. · Free Radical Biology and Medicine · 2010 · 245 citations

Neurophysiology, Medicine, Bioactive Metal +15

Hydrogen peroxide-induced neuronal apoptosis is associated with inhibition of protein phosphatase 2A and 5, leading to activation of MAPK pathway

Long Chen, Lei Liu, Jun Yin et al. · The International Journal of Biochemistry & Cell Biology · 2008 · 237 citations

Signal Transduction, Biochemistry, Lipid Peroxidation +11

Calcium Signaling Is Involved in Cadmium-Induced Neuronal Apoptosis via Induction of Reactive Oxygen Species and Activation of MAPK/mTOR Network

Baoshan Xu, Sujuan Chen, Yan Luo et al. · PLoS ONE · 2011 · 210 citations · Full text

Curcumin Disrupts the Mammalian Target of Rapamycin-Raptor Complex

Christopher S. Beevers, Long Chen, Lei Liu et al. · Cancer Research · 2009 · 200 citations · Full text

Signal Transduction, Chemoprevention Strategy, Signaling Pathway +13