Lei Chen

Exosomal transfer of tumor-associated macrophage-derived miR-21 confers cisplatin resistance in gastric cancer cells

Peiming Zheng, Lei Chen, Xiangliang Yuan et al. · Journal of Experimental & Clinical Cancer Research · 2017 · 640 citations · Full text

MicroRNA-mediated switching of chromatin-remodelling complexes in neural development

Andrew S. Yoo, Brett T. Staahl, Lei Chen et al. · Nature · 2009 · 619 citations · Full text

Chromatin, Developmental Biology, Chromatin Remodeling +5

NF-AT components define a family of transcription factors targeted in T-cell activation

Jeffrey P. Northrop, Steffan N. Ho, Lei Chen et al. · Nature · 1994 · 570 citations

Transcriptional Regulation, Signal Transduction, Functional Genomics +14

Camrelizumab versus investigator's choice of chemotherapy as second-line therapy for advanced or metastatic oesophageal squamous cell carcinoma (ESCORT): a multicentre, randomised, open-label, phase 3 study

Jing Huang, Jianming Xu, Yun Chen et al. · The Lancet Oncology · 2020 · 568 citations

Esophageal Cancer, Gastrointestinal Oncology, Medicine +10

Tumor-associated macrophages-derived exosomes promote the migration of gastric cancer cells by transfer of functional Apolipoprotein E

Peiming Zheng, Qin Luo, Weiwei Wang et al. · Cell Death and Disease · 2018 · 376 citations · Full text