Lei Chen

KIF23 activated Wnt/β-catenin signaling pathway through direct interaction with Amer1 in gastric cancer

Yi Liu, Hui Chen, Ping Dong et al. · Aging · 2020 · 122 citations · Full text

Cancer Biology, Tumor Biology, Transcriptional Regulation +17

Lipid accumulation in macrophages confers protumorigenic polarization and immunity in gastric cancer

Qin Luo, Naisheng Zheng, Li Jiang et al. · Cancer Science · 2020 · 115 citations · Full text

Suppression of Cyclin D1 by Hypoxia-Inducible Factor-1 via Direct Mechanism Inhibits the Proliferation and 5-Fluorouracil–Induced Apoptosis of A549 Cells

Wen Wen, Jin Ding, Wen Sun et al. · Cancer Research · 2010 · 83 citations

Cyclin D1, Apoptosis, Cell Death +22

Knockdown of hypoxia-inducible factor-1α in breast carcinoma MCF-7 cells results in reduced tumor growth and increased sensitivity to methotrexate

Jing Li, Mingxia Shi, Ying Cao et al. · Biochemical and Biophysical Research Communications · 2006 · 66 citations

Increased Sensitivity, Breast Oncology, Medicine +11

Elevated level of Interleukin-35 in colorectal cancer induces conversion of T cells into iTr35 by activating STAT1/STAT3

Yanhui Ma, Lei Chen, Guohua Xie et al. · Oncotarget · 2016 · 59 citations · Full text

T-regulatory Cell, Immunology, Immune Regulation +16