Detection of genomic G-quadruplexes in living cells using a small artificial protein

Ke‐wei Zheng, Jiayu Zhang, Yi-de He, +6

Nucleic Acids Research

Guanine-vacancy–bearing G-quadruplexes responsive to guanine derivatives

Xinmin Li, Ke‐wei Zheng, Jiayu Zhang, +5

Proceedings of the National Academy of Sciences

Co-transcriptional formation of DNA:RNA hybrid G-quadruplex and potential function as constitutional cis element for transcription control

Ke‐wei Zheng, Shan Xiao, Jiaquan Liu, +3

Nucleic Acids Research

GeneticsMolecular BiologyGene TranscriptionPotential Hq SequencesTranscriptional Regulation +16

D-arginine-loaded metal-organic frameworks nanoparticles sensitize osteosarcoma to radiotherapy

Chuanchao Du, Mengxue Zhou, Fei Jia, +8

Biomaterials

NanomedicineTumor TargetingTherapeutic NanomaterialsRadiation Oncology

Spaceflight and simulated microgravity suppresses macrophage development via altered RAS/ERK/NFκB and metabolic pathways

Lu Shi, Hongling Tian, Peng Wang, +4

Cellular and Molecular Immunology

InflammationMetabolic PathwaysMolecular PhysiologySignal TransductionCell Signaling +9

FABP5 controls macrophage alternative activation and allergic asthma by selectively programming long-chain unsaturated fatty acid metabolism

Yangxiao Hou, Wei Dong, Zhaoqi Zhang, +6

Cell Reports

AsthmaMitophagyInflammatory Lung DiseaseLung InflammationLipid Peroxidation +19

Mechanism and Manipulation of DNA:RNA Hybrid G-Quadruplex Formation in Transcription of G-Rich DNA

Jiayu Zhang, Ke‐wei Zheng, Shan Xiao, +2

Journal of the American Chemical Society

GeneticsMolecular BiologyMolecular GeneticsGene TranscriptionG-rich Dna +15

G-quadruplex structural variations in human genome associated with single-nucleotide variations and their impact on gene activity

Jia-yuan Gong, Cui-jiao Wen, Mingliang Tang, +9

Proceedings of the National Academy of Sciences

Bioinformatic analysis reveals an evolutional selection for DNA:RNA hybrid G-quadruplex structures as putative transcription regulatory elements in warm-blooded animals

Shan Xiao, Jiayu Zhang, Ke‐wei Zheng, +2

Nucleic Acids Research

Strand BiasGeneticsGenomic MechanismMolecular GeneticsGenomics +17

A competitive formation of DNA:RNA hybrid G-quadruplex is responsible to the mitochondrial transcription termination at the DNA replication priming site

Ke‐wei Zheng, Renyi Wu, Yi-de He, +5

Nucleic Acids Research

DnaGeneticsMolecular BiologyMolecular GeneticsHuman Mitochondrial Dna +15