Zhen Chen

Genome-wide CRISPR screens reveal synthetic lethality of RNASEH2 deficiency and ATR inhibition

Chao Wang, Gang Wang, Xu Feng et al. · Oncogene · 2018 · 133 citations

Off-target Effect, Genetics, Molecular Biology +8

Gadolinium metallofullerenol nanoparticles inhibit cancer metastasis through matrix metalloproteinase inhibition: imprisoning instead of poisoning cancer cells

Huan Meng, Gengmei Xing, Elvin Blanco et al. · Nanomedicine Nanotechnology Biology and Medicine · 2011 · 114 citations · Full text

Nanomedicine, Matrix Metalloproteinase Inhibition, Medicine +9

Chemotherapeutic drugs stimulate the release and recycling of extracellular vesicles to assist cancer cells in developing an urgent chemoresistance

Xiaokun Wang, Dongjuan Qiao, Likun Chen et al. · Molecular Cancer · 2019 · 73 citations · Full text

circ0000069 promotes cervical cancer cell proliferation and migration by inhibiting miR-4426

Zhen Chen, Kaijian Ling, Yingjun Zhu et al. · Biochemical and Biophysical Research Communications · 2021 · 41 citations

Cervical Cancer, Medicine, Cancer Cell Biology +6

ZNRD1 mediates resistance of gastric cancer cells to methotrexate by regulation of IMPDH2 and Bcl-2

Liu Hong, Taidong Qiao, Yu Han et al. · Biochemistry and Cell Biology · 2006 · 34 citations