Xiaobo Li

MFN2 suppresses cancer progression through inhibition of mTORC2/Akt signaling

Ke Xu, Guo Chen, Xiaobo Li et al. · Scientific Reports · 2017 · 160 citations · Full text

Medicine, Cancer Biology, Oncology +16

Gain-of-function mutations of <i>Ptpn11</i> (Shp2) cause aberrant mitosis and increase susceptibility to DNA damage-induced malignancies

Xia Liu, Hong Zheng, Xiaobo Li et al. · Proceedings of the National Academy of Sciences · 2016 · 49 citations · Full text

Life Sciences, Molecular Biology, Oncology +14

Small Molecule Inhibitor that Stabilizes the Autoinhibited Conformation of the Oncogenic Tyrosine Phosphatase SHP2

Xiaoqin Wu, Gang Xu, Xiaobo Li et al. · Journal of Medicinal Chemistry · 2018 · 49 citations · Full text

Medicine, Oncology, Pharmacology +17

Oncogenic Smurf1 promotes PTEN wild-type glioblastoma growth by mediating PTEN ubiquitylation

Xia Qin, Hanwen Zhang, Pei Zhang et al. · Oncogene · 2020 · 43 citations

Medicine, Cancer Biology, Oncology +15

Structure based design, synthesis and activity studies of small hybrid molecules as HDAC and G9a dual inhibitors

Lanlan Zang, Shukkoor Muhammed Kondengaden, Qing Zhang et al. · Oncotarget · 2017 · 35 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14