Ian D. Lightbown

Effects of mefloquine on cardiac contractility and electrical activity <i>in vivo</i>, in isolated cardiac preparations, and in single ventricular myocytes

Susan J. Coker, Andrew J. Batey, Ian D. Lightbown et al. · British Journal of Pharmacology · 2000 · 43 citations · Full text

Potentiation of halofantrine‐induced QTc prolongation by mefloquine: correlation with blood concentrations of halofantrine

Ian D. Lightbown, James P. Lambert, Geoffrey Edwards et al. · British Journal of Pharmacology · 2001 · 32 citations · Full text

Comparison of the acute cardiotoxicity of the antimalarial drug halofantrine <i>in vitro</i> and <i>in vivo</i> in anaesthetized guinea‐pigs

Andrew J. Batey, Ian D. Lightbown, James P. Lambert et al. · British Journal of Pharmacology · 1997 · 20 citations · Full text

Translation between in vitro inhibition of the cardiac Nav1.5 channel and pre-clinical and clinical QRS widening

Jason Cordes, Cheryl Li, Jeremy Dugas et al. · Journal of Pharmacological and Toxicological Methods · 2009 · 14 citations

Cardiac Muscle, Translational Medicine, Cardiomyopathy +10

A cross-species translational pharmacokinetic-pharmacodynamic evaluation of core body temperature reduction by the TRPM8 blocker PF-05105679

J Gosset, Kevin Beaumont, Tomomi Matsuura et al. · European Journal of Pharmaceutical Sciences · 2017 · 13 citations

Translational Medicine, Hyperthermia, Medicine +6