Role of lubricin and boundary lubrication in the prevention of chondrocyte apoptosis

Kimberly A. Waller, Ling X. Zhang, Khaled A. Elsaid, +3

Proceedings of the National Academy of Sciences

EngineeringPathologyCell DeathChondrocyte ApoptosisOrthopaedic Surgery +16

Prevention of cartilage degeneration and restoration of chondroprotection by lubricin tribosupplementation in the rat following anterior cruciate ligament transection

Gregory D. Jay, Braden C. Fleming, Bryn A. Watkins, +6

Arthritis & Rheumatism

Lubricin/Proteoglycan 4 Binding to CD44 Receptor: A Mechanism of the Suppression of Proinflammatory Cytokine–Induced Synoviocyte Proliferation by Lubricin

Afnan Al‐Sharif, Maha Jamal, Ling X. Zhang, +4

Arthritis & Rheumatology

The interaction of lubricin/proteoglycan 4 (PRG4) with toll-like receptors 2 and 4: an anti-inflammatory role of PRG4 in synovial fluid

Ali Alquraini, Steven Garguilo, Gerard G. M. D’Souza, +4

Arthritis Research & Therapy

InflammationRheumatologyAnti-inflammatoryAutoimmune DiseaseSynovial Fluid +8

Genistein Modulates Immune Responses and Increases Host Resistance to B16F10 Tumor in Adult Female B6C3F1 Mice

Tai L. Guo, J. A. McCay, Ling X. Zhang, +5

Journal of Nutrition

Tumor BiologyMedicineImmunologyTumor ImmunityPathology +8

Intra-articular Recombinant Human Proteoglycan 4 Mitigates Cartilage Damage After Destabilization of the Medial Meniscus in the Yucatan Minipig

Kimberly A. Waller, Kaitlyn E. Chin, Gregory D. Jay, +6

The American Journal of Sports Medicine

Recombinant human proteoglycan-4 reduces phagocytosis of urate crystals and downstream nuclear factor kappa B and inflammasome activation and production of cytokines and chemokines in human and murine macrophages

Marwa Qadri, Gregory D. Jay, Ling X. Zhang, +5

Arthritis Research & Therapy

Irisin promotes cardiac progenitor cell‐induced myocardial repair and functional improvement in infarcted heart

Yu Zhao, Jianguo Wang, Naohiro Yano, +9

Journal of Cellular Physiology

Proteoglycan-4 regulates fibroblast to myofibroblast transition and expression of fibrotic genes in the synovium

Marwa Qadri, Gregory D. Jay, Ling X. Zhang, +3

Arthritis Research & Therapy

Specific inhibition of HDAC4 in cardiac progenitor cells enhances myocardial repairs

Ling X. Zhang, Megan DeNicola, Xin Qin, +9

American Journal of Physiology-Cell Physiology