T Yokokura

Antitumor activity of 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothec in, a novel water-soluble derivative of camptothecin, against murine tumors.

Takehiko Kunimoto, Kazuo Nitta, Takashi Tanaka et al. · PubMed · 1987 · 412 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Metabolism and pharmacokinetics of the camptothecin analogue CPT-11 in the mouse.

N Kaneda, Hiroko Nagata, T Furuta et al. · PubMed · 1990 · 293 citations

Pharmacy, Pharmacokinetics, Pharmacology +11

Antitumor effect of CPT-11, a new derivative of camptothecin, against pleiotropic drug-resistant tumors in vitro and in vivo

T Tsuruo, Takeshi Matsuzaki, Miyuki Matsushita et al. · Cancer Chemotherapy and Pharmacology · 1988 · 213 citations

Medicine, Oncology, Pharmacology +13

Nonlinear pharmacokinetics of CPT-11 in rats.

N Kaneda, T Yokokura · PubMed · 1990 · 110 citations

Pharmacy, Pharmacokinetics, Pharmacology +12

Synthesis and Antitumor Activity of 20(S)-Camptothecin Derivatives: A-Ring Modified and 7,10-Disubstituted Camptothecins.

K Nokata, Hiroshi Nagata, T Furuta et al. · Chemical and Pharmaceutical Bulletin · 1991 · 68 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11