James L. Riley

CTLA-4 and PD-1 Receptors Inhibit T-Cell Activation by Distinct Mechanisms

Richard V. Parry, Jens M. Chemnitz, Kenneth A. Frauwirth et al. · Molecular and Cellular Biology · 2005 · 1.9K citations · Full text

Life Sciences, Immunology, Molecular Biology +17

The CD28 Signaling Pathway Regulates Glucose Metabolism

Kenneth A. Frauwirth, James L. Riley, Marian H. Harris et al. · Immunity · 2002 · 1.4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +10

SHP-1 and SHP-2 Associate with Immunoreceptor Tyrosine-Based Switch Motif of Programmed Death 1 upon Primary Human T Cell Stimulation, but Only Receptor Ligation Prevents T Cell Activation

Jens M. Chemnitz, Richard V. Parry, Kim E. Nichols et al. · The Journal of Immunology · 2004 · 1.2K citations · Full text

Life Sciences, Immunology, Molecular Biology +15

Chimeric Receptors Containing CD137 Signal Transduction Domains Mediate Enhanced Survival of T Cells and Increased Antileukemic Efficacy In Vivo

Michael C. Milone, Jonathan D. Fish, Carmine Carpenito et al. · Molecular Therapy · 2009 · 1.2K citations · Full text

Life Sciences, Immunology, Oncology +17

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

Elena Pérez, Jianbin Wang, Jeffrey C. Miller et al. · Nature Biotechnology · 2008 · 999 citations

Life Sciences, Molecular Biology, Molecular Genetics +12