Ilaria Gionfriddo

Mutant NPM1 Maintains the Leukemic State through HOX Expression

Lorenzo Brunetti, Michael C. Gundry, Daniele Sorcini et al. · Cancer Cell · 2018 · 317 citations

Life Sciences, Cancer Biology, Molecular Biology +12

Arsenic trioxide and all-trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1-mutated AML cells

Maria Paola Martelli, Ilaria Gionfriddo, Federica Mezzasoma et al. · Blood · 2015 · 147 citations · Full text

Medicine, Cancer Biology, Oncology +13

CD34+ cells from AML with mutated NPM1 harbor cytoplasmic mutated nucleophosmin and generate leukemia in immunocompromised mice

Maria Paola Martelli, Valentina Pettirossi, Christian Thiede et al. · Blood · 2010 · 115 citations · Full text

Medicine, Genetics, Oncology +15

Novel <i>NPM1</i> exon 5 mutations and gene fusions leading to aberrant cytoplasmic nucleophosmin in AML

Maria Paola Martelli, Roberta Rossi, Alessandra Venanzi et al. · Blood · 2021 · 56 citations · Full text

Life Sciences, Genetics, Molecular Genetics +4

Dactinomycin induces complete remission associated with nucleolar stress response in relapsed/refractory NPM1-mutated AML

Ilaria Gionfriddo, Lorenzo Brunetti, Federica Mezzasoma et al. · Leukemia · 2021 · 39 citations · Full text

Medicine, Oncology, Pharmacology +14