Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis

Feng Mei, Stephen P.J. Fancy, Yun‐An Shen, +13

Nature Medicine

Micropillar ArraysEngineeringMicrofabricationMedicineAnalytical Microsystems +9

Oligodendrocyte precursors migrate along vasculature in the developing nervous system

Hui‐Hsin Tsai, Jianqin Niu, Roeben N. Munji, +7

Science

Myelin degeneration and diminished myelin renewal contribute to age-related deficits in memory

Fei Wang, Shuyu Ren, Jing‐Fei Chen, +8

Nature Neuroscience

Alzheimer's DiseaseAgingBrain FunctionMyelin Renewal ContributeDementia +9

Aberrant oligodendroglial–vascular interactions disrupt the blood–brain barrier, triggering CNS inflammation

Jianqin Niu, Hui‐Hsin Tsai, Kimberly K. Hoi, +7

Nature Neuroscience

Glial BiologyInflammationHealth SciencesBlood–brain BarrierMedicine +11

Activation of Wnt/β-catenin pathway mitigates blood–brain barrier dysfunction in Alzheimer’s disease

Qi Wang, Xiaomin Huang, Yixun Su, +11

Brain

Wnt/β-catenin Pathway MitigatesBarrier DysfunctionAlzheimer ’Social SciencesNeuroinflammation +17

Clemastine rescues myelination defects and promotes functional recovery in hypoxic brain injury

Bruce Cree, Jianqin Niu, Kimberly K. Hoi, +12

Brain

Neurological DisorderMyelination DefectsDemyelinated LesionsSocial SciencesNeuroinflammation +18

Stage-Specific Deletion of Olig2 Conveys Opposing Functions on Differentiation and Maturation of Oligodendrocytes

Feng Mei, Hongkai Wang, Shubao Liu, +6

Journal of Neuroscience

Astrocyte endfoot formation controls the termination of oligodendrocyte precursor cell perivascular migration during development

Yixun Su, Xiaorui Wang, Yujian Yang, +14

Neuron

Connexin-based channels contribute to metabolic pathways in the oligodendroglial lineage

Jianqin Niu, Tao Li, Chenju Yi, +7

Journal of Cell Science

Pathological oligodendrocyte precursor cells revealed in human schizophrenic brains and trigger schizophrenia-like behaviors and synaptic defects in genetic animal model

Guangdan Yu, Yixun Su, Guo Chen, +15

Molecular Psychiatry