Emma Linderoth

TTI-621 (SIRPαFc): A CD47-Blocking Innate Immune Checkpoint Inhibitor with Broad Antitumor Activity and Minimal Erythrocyte Binding

Penka S. Petrova, Natasja Nielsen Viller, Mark Wong et al. · Clinical Cancer Research · 2016 · 276 citations

Life Sciences, Immunology, Oncology +17

Lysosome-mediated apoptosis is associated with cathepsin D-specific processing of bid at Phe24, Trp48, and Phe183.

Hanna Appelqvist, Ann‐Charlotte Johansson, Emma Linderoth et al. · PubMed · 2012 · 67 citations

Life Sciences, Cell Biology, Molecular Biology +16

TTI-621 (SIRPαFc), a CD47-blocking cancer immunotherapeutic, triggers phagocytosis of lymphoma cells by multiple polarized macrophage subsets

Gloria H. Y. Lin, Vien Chai, Vivian Lee et al. · PLoS ONE · 2017 · 62 citations · Full text

Life Sciences, Immunology, Oncology +17

Mig6 Is a Sensor of EGF Receptor Inactivation that Directly Activates c-Abl to Induce Apoptosis during Epithelial Homeostasis

Sarah Hopkins, Emma Linderoth, Oliver Hantschel et al. · Developmental Cell · 2012 · 56 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Activated Cdc42-associated Kinase 1 (Ack1) Is Required for Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Receptor Recruitment to Lipid Rafts and Induction of Cell Death

Emma Linderoth, Giulia Pilia, Nupam P. Mahajan et al. · Journal of Biological Chemistry · 2013 · 14 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17