Aldo Germani

Large scale multifactorial likelihood quantitative analysis of <i>BRCA1</i> and <i>BRCA2</i> variants: An ENIGMA resource to support clinical variant classification

Michael T. Parsons, Emma Tudini, Hongyan Li et al. · Human Mutation · 2019 · 148 citations · Full text

Genetics, Genetic Epidemiology, Pathology +25

A SMYD3 Small‐Molecule Inhibitor Impairing Cancer Cell Growth

Alessia Peserico, Aldo Germani, Paola Sanese et al. · Journal of Cellular Physiology · 2015 · 128 citations · Full text

Molecular and Functional Characterization of Three Different Postzygotic Mutations in PIK3CA-Related Overgrowth Spectrum (PROS) Patients: Effects on PI3K/AKT/mTOR Signaling and Sensitivity to PIK3 Inhibitors

Daria Carmela Loconte, Valentina Grossi, Cristina Bozzao et al. · PLoS ONE · 2015 · 80 citations · Full text

Targeted therapy against chemoresistant colorectal cancers: Inhibition of p38α modulates the effect of cisplatin in vitro and in vivo through the tumor suppressor FoxO3A

Aldo Germani, Antonio Matrone, Valentina Grossi et al. · Cancer Letters · 2013 · 54 citations

Oncology, Tumor Suppressor Foxo3a, Medicine +9

Blocking p38/ERK crosstalk affects colorectal cancer growth by inducing apoptosis in vitro and in preclinical mouse models

Fulvio Chiacchiera, Valentina Grossi, Marianna Cappellari et al. · Cancer Letters · 2012 · 49 citations

Colorectal Cancer Growth, P38/erk Crosstalk, Chemoprevention Strategy +12