John J. McGuire

Design and Synthesis of Classical and Nonclassical 6-Arylthio-2,4-diamino-5-ethylpyrrolo[2,3-<i>d</i>]pyrimidines as Antifolates

Aleem Gangjee, Yibin Zeng, Tina Talreja et al. · Journal of Medicinal Chemistry · 2007 · 280 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Enzymatic synthesis of folylpolyglutamates. Characterization of the reaction and its products.

John J. McGuire, Pearl Hsieh, James K. Coward et al. · Journal of Biological Chemistry · 1980 · 215 citations · Full text

Life Sciences, Biochemistry, Enzymology +7

Traditional pharmacological treatments for spasticity part II: General and regional treatments

Jean‐Michel Graciès, Patricia W. Nance, Elie Elovic et al. · Muscle & Nerve · 1997 · 210 citations

Medicine, Neurology, Rehabilitation Medicine +11

Endothelium-derived relaxing factors: A focus on endothelium-derived hyperpolarizing factor(s)

John J. McGuire, Hong Ding, Chris R. Triggle · Canadian Journal of Physiology and Pharmacology · 2001 · 174 citations

Life Sciences, Pharmacology, Physiology +12

Decreased folylpolyglutamate synthetase activity as a mechanism of methotrexate resistance in CCRF-CEM human leukemia sublines.

Diane E. McCloskey, John J. McGuire, Cynthia A. Russell et al. · Journal of Biological Chemistry · 1991 · 172 citations · Full text

Medicine, Oncology, Pharmacology +11