Cynthia A. Russell

Decreased folylpolyglutamate synthetase activity as a mechanism of methotrexate resistance in CCRF-CEM human leukemia sublines.

Diane E. McCloskey, John J. McGuire, Cynthia A. Russell et al. · Journal of Biological Chemistry · 1991 · 172 citations · Full text

Hematological Malignancy, Drug Resistance Analysis, Mtx Transport +12

Lipophilic methotrexate conjugates with antitumor activity

Rosario Pignatello, Giuseppina Spampinato, Valeria Sorrenti et al. · European Journal of Pharmaceutical Sciences · 2000 · 46 citations

Medicinal Chemistry, Lipophilic Methotrexate Conjugates, Polymer-drug Conjugate +2

Biochemical and growth inhibition studies of methotrexate and aminopterin analogues containing a tetrazole ring in place of the gamma-carboxyl group.

John J. McGuire, Cynthia A. Russell, W. Bolanowska et al. · PubMed · 1990 · 32 citations

Dhfr Activity, Pharmaceutical Science, Bioorganic Chemistry +19

Human Cytosolic and Mitochondrial Folylpolyglutamate Synthetase Are Electrophoretically Distinct

John J. McGuire, Cynthia A. Russell, Małgorzata Balińska · Journal of Biological Chemistry · 2000 · 23 citations · Full text

Chemoprevention Strategy, Immunology, Cancer Biology +20

Biochemical and biological properties of methotrexate analogs containing d-glutamic acid or d-erythro,threo-4-fluoroglutamic acid

John J. McGuire, W. Bolanowska, James K. Coward et al. · Biochemical Pharmacology · 1991 · 13 citations

Medicinal Chemistry, D-glutamic Acid, Threo-4-fluoroglutamic Acid +6