A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis

Ujjini H. Manjunatha, Sumiti Vinayak, Jennifer A. Zambriski, +23

Nature

PharmacologyMedicinePathologyCryptosporidium Pi

Development of an Orally Available and Central Nervous System (CNS) Penetrant <i>Toxoplasma gondii</i> Calcium-Dependent Protein Kinase 1 (<i>Tg</i>CDPK1) Inhibitor with Minimal Human Ether-a-go-go-Related Gene (hERG) Activity for the Treatment of <i>Toxoplasmosis</i>

Rama Subba Rao Vidadala, Kasey Rivas, Kayode K. Ojo, +23

Journal of Medicinal Chemistry

ImmunologyPathologyCell DeathPharmacotherapyImmunotherapy +15

Novel Bumped Kinase Inhibitors Are Safe and Effective Therapeutics in the Calf Clinical Model for Cryptosporidiosis

Deborah A. Schaefer, Dana P. Betzer, Kylie D. Smith, +15

The Journal of Infectious Diseases

Parasitic DiseaseAntiparasitic AgentMedicineParasitic ProtozoaPathogenesis +10

Microbiome sharing between children, livestock and household surfaces in western Kenya

Emily Mosites, Matt Sammons, Elkanah Otiang, +17

PLoS ONE

NutritionDysbiosisHousehold SurfacesWestern KenyaMicrobiome Biology +15

A Novel Piperazine-Based Drug Lead for Cryptosporidiosis from the Medicines for Malaria Venture Open-Access Malaria Box

Rajiv S. Jumani, Kovi Bessoff, Melissa S. Love, +10

Antimicrobial Agents and Chemotherapy

Cryptosporidium parvum: Determination of ID50 and the dose–response relationship in experimentally challenged dairy calves

Jennifer A. Zambriski, D.V. Nydam, Z.J. Wilcox, +3

Veterinary Parasitology

Animal PhysiologyDairy CalvesAnimal ScienceZoonotic DiseasePathogenesis +11

Effect of nitazoxanide on cryptosporidiosis in experimentally infected neonatal dairy calves

T. L. Ollivett, D.V. Nydam, Dwight D. Bowman, +4

Journal of Dairy Science

Description of fecal shedding of Cryptosporidium parvum oocysts in experimentally challenged dairy calves

Jennifer A. Zambriski, D.V. Nydam, Dwight D. Bowman, +7

Parasitology Research

Dairy CalvesAnimal ScienceZoonotic DiseasePathogenesisVeterinary Science +10

Antibody responses following administration of a Cryptosporidium parvum rCP15/60 vaccine to pregnant cattle

Alexandra J. Burton, D.V. Nydam, G. R. Jones, +6

Veterinary Parasitology

VaccinationVeterinary VaccineVaccine DevelopmentAnimal ScienceImmunology +6

A Comparison of Fecal Percent Dry Matter and Number of Cryptosporidium parvum Oocysts Shed to Observational Fecal Consistency Scoring in Dairy Calves

Mary L. Bellosa, D.V. Nydam, Janice L. Liotta, +3

Journal of Parasitology