Joseph E. Kaserman

hiPSC hepatocyte model demonstrates the role of unfolded protein response and inflammatory networks in α1-antitrypsin deficiency

Charis-Patricia Segeritz, S. Tamir Rashid, Miguel Cardoso de Brito et al. · Journal of Hepatology · 2018 · 66 citations · Full text

Adenine base editing reduces misfolded protein accumulation and toxicity in alpha-1 antitrypsin deficient patient iPSC-hepatocytes

Rhiannon B. Werder, Joseph E. Kaserman, Michael S. Packer et al. · Molecular Therapy · 2021 · 30 citations · Full text

Cell Death, Cell Regulation, Hepatotoxicity +22

A Highly Phenotyped Open Access Repository of Alpha-1 Antitrypsin Deficiency Pluripotent Stem Cells

Joseph E. Kaserman, Killian Hurley, Mark Dodge et al. · Stem Cell Reports · 2020 · 29 citations · Full text

Genetics, Genetic Epidemiology, Gene Characterization +18

Recombinant Lloviu virus as a tool to study viral replication and host responses

Adam J. Hume, Baylee Heiden, Judith Olejnik et al. · PLoS Pathogens · 2022 · 28 citations · Full text

Viral Replication, Virus Rescue, Lloviu Virus +14

Protocol for Directed Differentiation of Human Induced Pluripotent Stem Cells (iPSCs) to a Hepatic Lineage

Joseph E. Kaserman, Andrew A. Wilson · Methods in molecular biology · 2017 · 13 citations · Full text

Regenerative Medicine, Hepatic Lineage, Induced Pluripotent Stem Cell +13