P.M. van der Kraan

Synovial lining macrophages mediate osteophyte formation during experimental osteoarthritis

Arjen B. Blom, Peter L. E. M. van Lent, A. E. M. Holthuysen et al. · Osteoarthritis and Cartilage · 2004 · 373 citations · Full text

Medicine, Cell Biology, Immunology +11

Crucial role of macrophages in matrix metalloproteinase–mediated cartilage destruction during experimental osteoarthritis : Involvement of matrix metalloproteinase 3

Arjen B. Blom, P.L. van Lent, Sten F.W.M. Libregts et al. · Arthritis & Rheumatism · 2006 · 361 citations

Medicine, Pathobiology, Pathology +17

Transforming growth factor-beta 1 stimulates articular chondrocyte proteoglycan synthesis and induces osteophyte formation in the murine knee joint.

Henk M. van Beuningen, P.M. van der Kraan, OJ Arntz et al. · PubMed · 1994 · 358 citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +16

Increase in ALK1/ALK5 Ratio as a Cause for Elevated MMP-13 Expression in Osteoarthritis in Humans and Mice

E.N. Blaney Davidson, Dennis F.G. Remst, E.L. Vitters et al. · The Journal of Immunology · 2009 · 316 citations · Full text

Life Sciences, Immunology, Developmental Signaling +4

Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation

Andrew C. Bakker, Fons A. J. van de Loo, Henk M. van Beuningen et al. · Osteoarthritis and Cartilage · 2001 · 294 citations · Full text

Medicine, Orthopaedic Surgery, Orthopedic Surgery +11