Nien-Du Yang

Two-stage electro–mechanical coupling of a KV channel in voltage-dependent activation

Panpan Hou, Po Wei Kang, Audrey Deyawe Kongmeneck et al. · Nature Communications · 2020 · 72 citations · Full text

Natural Sciences, Biophysics, Physiology +17

Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state

Keenan C. Taylor, Po Wei Kang, Panpan Hou et al. · eLife · 2020 · 56 citations · Full text

Natural Sciences, Biophysics, Molecular Biology +15

Pharmacologic Characterization of LTGO-33, a Selective Small Molecule Inhibitor of the Voltage-Gated Sodium Channel NaV1.8 with a Unique Mechanism of Action

John M. Gilchrist, Nien-Du Yang, Victoria Jiang et al. · Molecular Pharmacology · 2024 · 38 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

A PIP2 substitute mediates voltage sensor-pore coupling in KCNQ activation

Yongfeng Liu, Xianjin Xu, Junyuan Gao et al. · Communications Biology · 2020 · 37 citations · Full text

Medicine, Biochemistry, Pharmacology +17

Electro-mechanical coupling of KCNQ channels is a target of epilepsy-associated mutations and retigabine

Nien-Du Yang, Richard Kanyo, Lu Zhao et al. · Science Advances · 2022 · 16 citations · Full text

Life Sciences, Pharmacology, Physiology +17