Jan Benada

Gain-of-function mutations of PPM1D/Wip1 impair the p53-dependent G1 checkpoint

Petra Kleiblová, Indra A. Shaltiël, Jan Benada et al. · The Journal of Cell Biology · 2013 · 166 citations · Full text

Genome Instability, P53-dependent G1 Checkpoint, Medicine +11

Cancer cells use self-inflicted DNA breaks to evade growth limits imposed by genotoxic stress

Brian D. Larsen, Jan Benada, Philip Yuk Kwong Yung et al. · Science · 2022 · 79 citations

Dna Damage, Genetics, Genotoxic Therapy +20

Physiological Tolerance to ssDNA Enables Strand Uncoupling during DNA Replication

Amaia Ercilla, Jan Benada, Sampath Amitash et al. · Cell Reports · 2020 · 78 citations · Full text

Chromatin, Genome Instability, Natural Sciences +7

Polo-like kinase 1 inhibits DNA damage response during mitosis

Jan Benada, Kamila Burdová, Tomáš Liďák et al. · Cell Cycle · 2015 · 74 citations · Full text

Chromatin, Genome Instability, Cell Regulation +12

Inhibition of WIP1 phosphatase sensitizes breast cancer cells to genotoxic stress and to MDM2 antagonist nutlin-3

Soňa Pecháčková, Kamila Burdová, Jan Benada et al. · Oncotarget · 2016 · 71 citations · Full text