Kyle T. Pfaffenbach

The critical role of GRP78 in physiologic and pathologic stress

Kyle T. Pfaffenbach, Amy S. Lee · Current Opinion in Cell Biology · 2010 · 332 citations

Stress Hormone, Stress, Critical Role +6

Linking endoplasmic reticulum stress to cell death in hepatocytes: roles of C/EBP homologous protein and chemical chaperones in palmitate-mediated cell death

Kyle T. Pfaffenbach, Christopher L. Gentile, Angela M. Nivala et al. · American Journal of Physiology-Endocrinology and Metabolism · 2010 · 164 citations

Mitophagy, Chop Gene, Apoptosis +25

Experimental evidence for therapeutic potential of taurine in the treatment of nonalcoholic fatty liver disease

Christopher L. Gentile, Angela M. Nivala, Jon C. Gonzales et al. · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 2011 · 127 citations

Therapeutic Potential, Lipid Peroxidation, Fatty Liver Disease +19

GRP78 as a regulator of liver steatosis and cancer progression mediated by loss of the tumor suppressor PTEN

W-T Chen, Ge Zhu, Kyle T. Pfaffenbach et al. · Oncogene · 2013 · 75 citations · Full text

Tumor Biology, Hepatology, Medicine +12

Liver-specific knockout of GRP94 in mice disrupts cell adhesion, activates liver progenitor cells, and accelerates liver tumorigenesis

Wan‐Ting Chen, Chun-Chih Tseng, Kyle T. Pfaffenbach et al. · Hepatology · 2013 · 67 citations · Full text