Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation

Luc H. Boudreau, Anne‐Claire Duchez, Nathalie Cloutier, +22

Blood

Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A ₂ -IIA

Anne‐Claire Duchez, Luc H. Boudreau, Gajendra S. Naika, +17

Proceedings of the National Academy of Sciences

Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration

Nathalie Cloutier, Isabelle Allaeys, Geneviève Marcoux, +21

Proceedings of the National Academy of Sciences

Influenza virus H1N1 activates platelets through FcγRIIA signaling and thrombin generation

Éric Boilard, Guillaume Paré, Matthieu Rousseau, +5

Blood

The 20 <i>S</i> proteasome core, active within apoptotic exosome-like vesicles, induces autoantibody production and accelerates rejection

Mélanie Dieudé, Christina Bell, Julie Turgeon, +23

Science Translational Medicine

Folate: effects on carcinogenesis and the potential for cancer chemoprevention.

Joel B. Mason, Tania Lévesque

PubMed

Chemoprevention StrategyGastroenterologyPathologyCancer BiologyTumor Biology +15

Platelets release mitochondrial antigens in systemic lupus erythematosus

Imène Melki, Isabelle Allaeys, Nicolas Tessandier, +19

Science Translational Medicine

ImmunologyMitochondrial BiologyImmune SystemMitochondrial BiogenesisHematology +18

Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules

Geneviève Marcoux, Audrée Laroche, Stephan Hasse, +21

Blood

Detection and Quantification of Microparticles from Different Cellular Lineages Using Flow Cytometry. Evaluation of the Impact of Secreted Phospholipase A2 on Microparticle Assessment

Matthieu Rousseau, Clémence Belleannée, Anne‐Claire Duchez, +9

PLoS ONE

Immunocytochemical TechniqueEngineeringBlood CellPathologyMicroparticle Assessment +19

Microparticle and mitochondrial release during extended storage of different types of platelet concentrates

Geneviève Marcoux, Anne‐Claire Duchez, Matthieu Rousseau, +4

Platelets

ThrombopoiesisThrombosisMitochondrial ReleaseEngineeringMitochondrial Function +13