Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation

Luc H. Boudreau, Anne‐Claire Duchez, Nathalie Cloutier, +22

Blood

Activated platelets can deliver mRNA regulatory Ago2•microRNA complexes to endothelial cells via microparticles

Benoit Laffont, Aurélie Corduan, Hélène Plé, +4

Blood

Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A ₂ -IIA

Anne‐Claire Duchez, Luc H. Boudreau, Gajendra S. Naika, +17

Proceedings of the National Academy of Sciences

The 20 <i>S</i> proteasome core, active within apoptotic exosome-like vesicles, induces autoantibody production and accelerates rejection

Mélanie Dieudé, Christina Bell, Julie Turgeon, +23

Science Translational Medicine

Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling

Yi Jin, Lars Muhl, Mikhail Burmakin, +5

Nature Cell Biology

Developmental BiologyAngiogenesisTumor MicroenvironmentVascular AdaptationMorphogenesis +8

Platelet microparticles reprogram macrophage gene expression and function

Matthieu Rousseau, Anne‐Claire Duchez, Chan Ho Chris Lee, +4

Thrombosis and Haemostasis

ImmunologyPlatelet MpsInflammationHematologyNeuroimmunology +19

Delivery of MicroRNAs by Chitosan Nanoparticles to Functionally Alter Macrophage Cholesterol Efflux <i>in Vitro</i> and <i>in Vivo</i>

My-Anh Nguyen, Hailey Wyatt, Leah C. Susser, +10

ACS Nano

NanoparticlesNanomedicineNanoparticle CharacterizationEngineeringCardiovascular Disease +12

Revealing the diversity of extracellular vesicles using high-dimensional flow cytometry analyses

Geneviève Marcoux, Anne‐Claire Duchez, Nathalie Cloutier, +3

Scientific Reports

Detection and Quantification of Microparticles from Different Cellular Lineages Using Flow Cytometry. Evaluation of the Impact of Secreted Phospholipase A2 on Microparticle Assessment

Matthieu Rousseau, Clémence Belleannée, Anne‐Claire Duchez, +9

PLoS ONE

Immunocytochemical TechniqueEngineeringBlood CellPathologyMicroparticle Assessment +19

Microparticle and mitochondrial release during extended storage of different types of platelet concentrates

Geneviève Marcoux, Anne‐Claire Duchez, Matthieu Rousseau, +4

Platelets

ThrombopoiesisThrombosisMitochondrial ReleaseEngineeringMitochondrial Function +13