Platelets Can Associate With SARS-CoV-2 RNA and Are Hyperactivated in COVID-19

Younes Zaid, Florian Puhm, Isabelle Allaeys, +17

Circulation Research

Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A ₂ -IIA

Anne‐Claire Duchez, Luc H. Boudreau, Gajendra S. Naika, +17

Proceedings of the National Academy of Sciences

Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration

Nathalie Cloutier, Isabelle Allaeys, Geneviève Marcoux, +21

Proceedings of the National Academy of Sciences

Platelets release mitochondrial antigens in systemic lupus erythematosus

Imène Melki, Isabelle Allaeys, Nicolas Tessandier, +19

Science Translational Medicine

ImmunologyMitochondrial BiologyImmune SystemMitochondrial BiogenesisHematology +18

Platelet-derived extracellular vesicles infiltrate and modify the bone marrow during inflammation

Shauna L. French, Kirill R. Butov, Isabelle Allaeys, +11

Blood Advances

Platelet‐derived extracellular vesicles convey mitochondrial DAMPs in platelet concentrates and their levels are associated with adverse reactions

Geneviève Marcoux, Audrey Magron, Caroline Sut, +9

Transfusion

Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules

Geneviève Marcoux, Audrée Laroche, Stephan Hasse, +21

Blood

Anti-mitochondrial autoantibodies in systemic lupus erythematosus and their association with disease manifestations

Yann Becker, Renée-Claude Loignon, Anne‐Sophie Julien, +18

Scientific Reports

Platelet activation by SARS-CoV-2 implicates the release of active tissue factor by infected cells

Florian Puhm, Isabelle Allaeys, Émile Lacasse, +11

Blood Advances

Autoantibodies in Systemic Lupus Erythematosus Target Mitochondrial RNA

Yann Becker, Geneviève Marcoux, Isabelle Allaeys, +7

Frontiers in Immunology