Megan F. Duffy

Best Practices for Generating and Using Alpha-Synuclein Pre-Formed Fibrils to Model Parkinson’s Disease in Rodents

Nicole K. Polinski, Laura A. Volpicelli‐Daley, Caryl E. Sortwell et al. · Journal of Parkinson s Disease · 2018 · 289 citations · Full text

Neurodegenerative Diseases, Systems Biology, Alpha-synuclein Pre-formed Fibrils +13

Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration

Megan F. Duffy, Timothy J. Collier, Joseph R. Patterson et al. · Journal of Neuroinflammation · 2018 · 196 citations · Full text

Time course and magnitude of alpha-synuclein inclusion formation and nigrostriatal degeneration in the rat model of synucleinopathy triggered by intrastriatal α-synuclein preformed fibrils

Joseph R. Patterson, Megan F. Duffy, Christopher J. Kemp et al. · Neurobiology of Disease · 2019 · 104 citations · Full text

Synaptic Transmission, Neurochemical Biomarkers, Clinical Neuroscience +19

Quality Over Quantity: Advantages of Using Alpha-Synuclein Preformed Fibril Triggered Synucleinopathy to Model Idiopathic Parkinson’s Disease

Megan F. Duffy, Timothy J. Collier, Joseph R. Patterson et al. · Frontiers in Neuroscience · 2018 · 56 citations · Full text

Generation of Alpha-Synuclein Preformed Fibrils from Monomers and Use In Vivo

Joseph R. Patterson, Nicole K. Polinski, Megan F. Duffy et al. · Journal of Visualized Experiments · 2019 · 53 citations · Full text

Engineering, Molecular Biology, Cell Culture +16