Joseph R. Patterson

Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration

Megan F. Duffy, Timothy J. Collier, Joseph R. Patterson et al. · Journal of Neuroinflammation · 2018 · 196 citations · Full text

Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology

Fredric P. Manfredsson, Kelvin C. Luk, Matthew J. Benskey et al. · Neurobiology of Disease · 2018 · 178 citations · Full text

Neurobiology Of Disease, Enteric Nervous System, Experimental Neuropathology +9

Time course and magnitude of alpha-synuclein inclusion formation and nigrostriatal degeneration in the rat model of synucleinopathy triggered by intrastriatal α-synuclein preformed fibrils

Joseph R. Patterson, Megan F. Duffy, Christopher J. Kemp et al. · Neurobiology of Disease · 2019 · 104 citations · Full text

Synaptic Transmission, Neurochemical Biomarkers, Clinical Neuroscience +19

Quality Over Quantity: Advantages of Using Alpha-Synuclein Preformed Fibril Triggered Synucleinopathy to Model Idiopathic Parkinson’s Disease

Megan F. Duffy, Timothy J. Collier, Joseph R. Patterson et al. · Frontiers in Neuroscience · 2018 · 56 citations · Full text

Generation of Alpha-Synuclein Preformed Fibrils from Monomers and Use In Vivo

Joseph R. Patterson, Nicole K. Polinski, Megan F. Duffy et al. · Journal of Visualized Experiments · 2019 · 53 citations · Full text

Engineering, Molecular Biology, Cell Culture +16