Allen G. Li

Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974

Jun Liu, Shifeng Pan, Mindy H. Hsieh et al. · Proceedings of the National Academy of Sciences · 2013 · 835 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Targeting Bcr–Abl by combining allosteric with ATP-binding-site inhibitors

Jianming Zhang, Francisco Adrián, Wolfgang Jahnke et al. · Nature · 2010 · 599 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Synthesis, Structure–Activity Relationships, and in Vivo Efficacy of the Novel Potent and Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor 5-Chloro-<i>N</i>2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-<i>N</i>4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) Currently in Phase 1 and Phase 2 Clinical Trials

Thomas H. Marsilje, Wei Pei, Bei Chen et al. · Journal of Medicinal Chemistry · 2013 · 412 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +16

Signaling Mechanism of TGF-β1 in Prevention of Renal Inflammation

Wansheng Wang, Xiao Ru Huang, Allen G. Li et al. · Journal of the American Society of Nephrology · 2005 · 234 citations

Medicine, Immunology, Pathology +17

Latent TGFβ1 overexpression in keratinocytes results in a severe psoriasis‐like skin disorder

Allen G. Li, Donna Wang, Xin‐Hua Feng et al. · The EMBO Journal · 2004 · 222 citations · Full text

Medicine, Dermatology, Immunology +12