Patrick O. Hanafin

Development of a Minimal Physiologically-Based Pharmacokinetic Model to Simulate Lung Exposure in Humans Following Oral Administration of Ivermectin for COVID-19 Drug Repurposing

Brian Jermain, Patrick O. Hanafin, Yanguang Cao et al. · Journal of Pharmaceutical Sciences · 2020 · 45 citations · Full text

Assessing the predictive performance of population pharmacokinetic models for intravenous polymyxin B in critically ill patients

Patrick O. Hanafin, Roger L. Nation, Marc H. Scheetz et al. · CPT Pharmacometrics & Systems Pharmacology · 2021 · 31 citations · Full text

A mechanism‐based pharmacokinetic model of remdesivir leveraging interspecies scaling to simulate COVID‐19 treatment in humans

Patrick O. Hanafin, Brian Jermain, Anthony J. Hickey et al. · CPT Pharmacometrics & Systems Pharmacology · 2020 · 29 citations · Full text

A population pharmacokinetic model of polymyxin B based on prospective clinical data to inform dosing in hospitalized patients

Patrick O. Hanafin, Andrea Lay‐Hoon Kwa, Alexandre Prehn Zavascki et al. · Clinical Microbiology and Infection · 2023 · 21 citations · Full text

Precision Dosing, Population Pharmacokinetic Model, Pharmacology +7

Evaluation Strategies for Triple‐Drug Combinations against Carbapenemase‐Producing <i>Klebsiella Pneumoniae</i> in an <i>In Vitro</i> Hollow‐Fiber Infection Model

Estefany Garcia, John K. Diep, Rajnikant Sharma et al. · Clinical Pharmacology & Therapeutics · 2021 · 19 citations · Full text