Toshinobu Nakamura

5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming

Mark Wossidlo, Toshinobu Nakamura, Konstantin Lepikhov et al. · Nature Communications · 2011 · 778 citations · Full text

Chromatin, Chromatin Remodeling, Epigenetic Change +7

PGC7/Stella protects against DNA demethylation in early embryogenesis

Toshinobu Nakamura, Yoshikazu Arai, Hiroki Umehara et al. · Nature Cell Biology · 2006 · 570 citations

Developmental Biology, Genetics, Dna Demethylation +6

PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos

Toshinobu Nakamura, Yu-Jung Liu, Hiroyuki Nakashima et al. · Nature · 2012 · 447 citations

Chromatin, Embryology, Developmental Biology +14

High-affinity monoclonal IgA regulates gut microbiota and prevents colitis in mice

Shinsaku Okai, Fumihito Usui, Shuhei Yokota et al. · Nature Microbiology · 2016 · 159 citations

Inflammation, Dysbiosis, Mucosal Immunology +12

RNAi-mediated knockdown of <i>Xist</i> can rescue the impaired postimplantation development of cloned mouse embryos

Shogo Matoba, Kimiko Inoue, Takashi Kohda et al. · Proceedings of the National Academy of Sciences · 2011 · 149 citations

Engineering, Rnai-mediated Knockdown, Genetics +23