Alexander R. Harmer

Scientific review and recommendations on preclinical cardiovascular safety evaluation of biologics

Hugo M. Vargas, Alan Bass, Alexander Breidenbach et al. · Journal of Pharmacological and Toxicological Methods · 2008 · 124 citations

Pharmacy, Cardiology, Clinical Sciences +11

Optimisation and validation of a medium-throughput electrophysiology-based hNav1.5 assay using IonWorks™

Alexander R. Harmer, Najah Abi‐Gerges, Alison Easter et al. · Journal of Pharmacological and Toxicological Methods · 2007 · 120 citations

Engineering, Bioengineering, Pharmacology +10

Assessment of Cardiomyocyte Contraction in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Amy Pointon, Alexander R. Harmer, Ian L. Dale et al. · Toxicological Sciences · 2014 · 102 citations · Full text

Medicine, Cardiology, Pharmacology +13

Design and optimisation of dendrimer-conjugated Bcl-2/xL inhibitor, AZD0466, with improved therapeutic index for cancer therapy

Claire Patterson, Srividya B. Balachander, Iain Grant et al. · Communications Biology · 2021 · 95 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Acetylcholine-evoked calcium mobilization and ion channel activation in human labial gland acinar cells from patients with primary Sjögren's syndrome

Luke Dawson, E A Field, Alexander R. Harmer et al. · Clinical & Experimental Immunology · 2001 · 60 citations · Full text

Life Sciences, Endocrinology, Immunology +17