Menthol Attenuates Respiratory Irritation and Elevates Blood Cotinine in Cigarette Smoke Exposed Mice

Michael Ha, Gregory J. Smith, Joseph A. Cichocki, +5

PLoS ONE

Tobacco ControlNicotine AbsorptionLung InflammationMedicineNicotine +13

A Validated Hybrid Computational Fluid Dynamics-Physiologically Based Pharmacokinetic Model for Respiratory Tract Vapor Absorption in the Human and Rat and Its Application to Inhalation Dosimetry of Diacetyl

Eric Gloede, Joseph A. Cichocki, Joshua B. Baldino, +1

Toxicological Sciences

Lung InflammationGas Exchange ProcessPhysiologically-based Pharmacokinetic ModelingRespiratory ToxicologyPulmonary Pharmacology +19

Effects of pirfenidone in acute and sub-chronic liver fibrosis, and an initiation-promotion cancer model in the mouse

Oleksii Seniutkin, Shinji Furuya, Yu‐Syuan Luo, +7

Toxicology and Applied Pharmacology

Sub-chronic Liver FibrosisFibrosisOncologyHepatologyInitiation-promotion Cancer Model +11

Characterization of Variability in Toxicokinetics and Toxicodynamics of Tetrachloroethylene Using the Collaborative Cross Mouse Population

Joseph A. Cichocki, Shinji Furuya, Abhishek Venkatratnam, +7

Environmental Health Perspectives

Editor’s Highlight: Comparative Dose-Response Analysis of Liver and Kidney Transcriptomic Effects of Trichloroethylene and Tetrachloroethylene in B6C3F1 Mouse

Yi‐Hui Zhou, Joseph A. Cichocki, Valerie Y. Soldatow, +7

Toxicological Sciences

Toxicological MechanismOxidative StressEnvironmental ChemistryB6c3f1 MouseKidney Transcriptomic Effects +21

Using Collaborative Cross Mouse Population to Fill Data Gaps in Risk Assessment: A Case Study of Population-Based Analysis of Toxicokinetics and Kidney Toxicodynamics of Tetrachloroethylene

Yu‐Syuan Luo, Joseph A. Cichocki, Nan‐Hung Hsieh, +5

Environmental Health Perspectives

Histopathological and Molecular Signatures of a Mouse Model of Acute-on-Chronic Alcoholic Liver Injury Demonstrate Concordance With Human Alcoholic Hepatitis

Shinji Furuya, Joseph A. Cichocki, Kranti Konganti, +9

Toxicological Sciences

Impact of Nonalcoholic Fatty Liver Disease on Toxicokinetics of Tetrachloroethylene in Mice

Joseph A. Cichocki, Shinji Furuya, Kranti Konganti, +7

Journal of Pharmacology and Experimental Therapeutics

Tissue Sensitivity of the Rat Upper and Lower Extrapulmonary Airways to the Inhaled Electrophilic Air Pollutants Diacetyl and Acrolein

Joseph A. Cichocki, Gregory J. Smith, John B. Morris

Toxicological Sciences

AsthmaAcute Lung InjuryAntioxidant GenesInflammatory Lung DiseaseLung Inflammation +20

Cardiovascular microphysiological systems (CVMPS) for safety studies – a pharma perspective

Amy Pointon, Jonathan Maher, Myrtle Davis, +9

Lab on a Chip