Lan Ye

SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function

Nathan L. Price, Ana P. Gomes, Alvin J. Y. Ling et al. · Cell Metabolism · 2012 · 1.5K citations · Full text

Reductive Stress, Biochemistry, Mitochondrial Function +8

Rapamycin has a biphasic effect on insulin sensitivity in C2C12 myotubes due to sequential disruption of mTORC1 and mTORC2

Lan Ye, Behzad Varamini, Dudley W. Lamming et al. · Frontiers in Genetics · 2012 · 81 citations · Full text

Sequential Disruption, Insulin Signaling, Mtorc2 Disruption +22

Caspase-11–mediated enteric neuronal pyroptosis underlies Western diet–induced colonic dysmotility

Lan Ye, Ge Li, Anna Goebel et al. · Journal of Clinical Investigation · 2020 · 78 citations · Full text

Inflammation, Enteric Neuronal Degeneration, Saturated Fatty Acids +15

Young and old genetically heterogeneous <scp>HET</scp>3 mice on a rapamycin diet are glucose intolerant but insulin sensitive

Dudley W. Lamming, Lan Ye, Clinton M. Astle et al. · Aging Cell · 2013 · 73 citations · Full text

Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity

Dudley W. Lamming, Lan Ye, Pekka Katajisto et al. · Science · 2012 · 68 citations · Full text

Rapamycin Complex 1, Metabolic Remodeling, Caloric Restriction +19