Clinton M. Astle

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

Randy Strong, Z. Dave Sharp, James F. Nelson et al. · Nature · 2009 · 3.7K citations · Full text

Education, Genetics, Nutrition +15

Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice

Richard A. Miller, Clinton M. Astle, Joseph A. Baur et al. · The Journals of Gerontology Series A · 2010 · 913 citations · Full text

Education, Pharmacology, Pharmacotherapy +16

Rapamycin‐mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction

Richard A. Miller, David E. Harrison, Clinton M. Astle et al. · Aging Cell · 2013 · 635 citations · Full text

Education, Endocrinology, Pharmacology +17

Acarbose, 17‐α‐estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males

Randy Strong, David B. Allison, Bruce N. Ames et al. · Aging Cell · 2013 · 464 citations · Full text

Education, Endocrinology, Physiology +17

Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α‐glucosidase inhibitor or a Nrf2‐inducer

Randy Strong, Richard A. Miller, Adam Antebi et al. · Aging Cell · 2016 · 377 citations · Full text

Education, Endocrinology, Pharmacology +17