James A. Pearson

NLRP3 deficiency protects from type 1 diabetes through the regulation of chemotaxis into the pancreatic islets

Changyun Hu, Heyuan Ding, Yangyang Li et al. · Proceedings of the National Academy of Sciences · 2015 · 133 citations

Gut microbial metabolites alter IgA immunity in type 1 diabetes

Juan Huang, James A. Pearson, Jian Peng et al. · JCI Insight · 2020 · 84 citations · Full text

Dysbiosis, Immunology, Gut Microbiota +16

TRIF deficiency protects non-obese diabetic mice from type 1 diabetes by modulating the gut microbiota and dendritic cells

Elke Gülden, Chao Chen, Ningwen Tai et al. · Journal of Autoimmunity · 2018 · 53 citations · Full text

Obesity, Metabolic Syndrome, Inflammation +11

Norovirus Changes Susceptibility to Type 1 Diabetes by Altering Intestinal Microbiota and Immune Cell Functions

James A. Pearson, Ningwen Tai, Dilrukshi Ekanayake‐Alper et al. · Frontiers in Immunology · 2019 · 41 citations · Full text

Toll-like receptor 9 negatively regulates pancreatic islet beta cell growth and function in a mouse model of type 1 diabetes

Mengju Liu, Jian Peng, Ningwen Tai et al. · Diabetologia · 2018 · 35 citations · Full text