Kazuo Komano

Total Synthesis of Ciguatoxin and 51-HydroxyCTX3C

Masayuki Inoue, Keisuke Miyazaki, Yuuki Ishihara et al. · Journal of the American Chemical Society · 2006 · 95 citations

Natural Sciences, Chemistry, Toxicology +15

Stereocontrolled synthesis of the ABCDE ring moiety of ciguatoxin CTX3C

Shöji Kobayashi, Yusuke Takahashi, Kazuo Komano et al. · Tetrahedron · 2004 · 43 citations

Pharmacy, Medicinal Chemistry, Pharmacology +7

Total Synthesis of the Maduropeptin Chromophore Aglycon

Kazuo Komano, Satoshi Shimamura, Masayuki Inoue et al. · Journal of the American Chemical Society · 2007 · 43 citations

Pharmacy, Biochemistry, Medicinal Chemistry +13

Rational Design of Novel 1,3-Oxazine Based β-Secretase (BACE1) Inhibitors: Incorporation of a Double Bond To Reduce P-gp Efflux Leading to Robust Aβ Reduction in the Brain

Kouki Fuchino, Yasunori Mitsuoka, Moriyasu Masui et al. · Journal of Medicinal Chemistry · 2018 · 34 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of Potent and Centrally Active 6-Substituted 5-Fluoro-1,3-dihydro-oxazine β-Secretase (BACE1) Inhibitors via Active Conformation Stabilization

Kenji Nakahara, Kouki Fuchino, Kazuo Komano et al. · Journal of Medicinal Chemistry · 2018 · 34 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17