Concepedia

Darshan Makhey

DM

7

Publications

489

Citations

7

H-Index

1996

Active since

Affiliations

Rutgers, The State University of New Jersey(Current)

Johnson University

Darshan Makhey is an author at Rutgers, The State University of New Jersey specializing in medicine, pharmacology, and toxicology.

Top concepts

Publications per year

1996–2003

7

Publications

7

Identification of topoisomerase I as the cytotoxic target of the protoberberine alkaloid coralyne.

Barbara Gatto, M M Sanders, C. Yu et al. · PubMed · 1996 · 129 citations

, , +14

Minor Groove-Directed and Intercalative Ligand−DNA Interactions in the Poisoning of Human DNA Topoisomerase I by Protoberberine Analogs

Daniel S. Pilch, Chiang Yu, Darshan Makhey et al. · Biochemistry · 1997 · 110 citations

Coralyne and related compounds as mammalian topoisomerase I and topoisomerase II poisons

Darshan Makhey, Barbara Gatto, Chiang Yu et al. · Bioorganic & Medicinal Chemistry · 1996 · 90 citations

, , +6

Selective cytotoxicity of topoisomerase-directed protoberberines against glioblastoma cells

M M Sanders, AngelaA Liu, Tsai‐Kun Li et al. · Biochemical Pharmacology · 1998 · 61 citations

, , +5

Substituted benzo[i]phenanthridines as mammalian topoisomerase-Targeting agents

Darshan Makhey, Dajie Li, Baoping Zhao et al. · Bioorganic & Medicinal Chemistry · 2003 · 40 citations

, , +5

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