Essential role of HDAC6 in the regulation of PD‐L1 in melanoma

Maritza Lienlaf, Patricio Perez-Villarroel, Tessa Knox, +16

Molecular Oncology

A B-Box 2 Surface Patch Important for TRIM5α Self-Association, Capsid Binding Avidity, and Retrovirus Restriction

Felipe Diaz‐Griffero, Xu-rong Qin, Fumiaki Hayashi, +6

Journal of Virology

Divergent roles of histone deacetylase 6 (HDAC6) and histone deacetylase 11 (HDAC11) on the transcriptional regulation of IL10 in antigen presenting cells

Fengdong Cheng, Maritza Lienlaf, Patricio Perez-Villarroel, +11

Molecular Immunology

ChromatinTranscriptional RegulationAutoimmune DiseaseChromatin RemodelingImmunology +8

Targeting histone deacetylase 6 mediates a dual anti‐melanoma effect: Enhanced antitumor immunity and impaired cell proliferation

Karrune Woan, Maritza Lienlaf, P. Perez-Villaroel, +20

Molecular Oncology

A Novel Role for Histone Deacetylase 6 in the Regulation of the Tolerogenic STAT3/IL-10 Pathway in APCs

Fengdong Cheng, Maritza Lienlaf, Hongwei Wang, +14

The Journal of Immunology

Epigenetic ChangeSelective Hdac6 InhibitorImmunologyImmune RegulationImmunologic Mechanism +26

The antimelanoma activity of the histone deacetylase inhibitor panobinostat (LBH589) is mediated by direct tumor cytotoxicity and increased tumor immunogenicity

David Woods, Karrune Woan, Fengdong Cheng, +9

Melanoma Research

ImmunologyPathologyDermatologyImmunotherapyMelanoma Cells +18

TNPO3 Is Required for HIV-1 Replication after Nuclear Import but prior to Integration and Binds the HIV-1 Core

José Carlos Valle‐Casuso, Francesca Di Nunzio, Yang Yang, +6

Journal of Virology

Viral ReplicationNuclear ImportHuman RetrovirusHiv-1 BlockImmunology +10

Contribution of E3-Ubiquitin Ligase Activity to HIV-1 Restriction by TRIM5α _rh : Structure of the RING Domain of TRIM5α

Maritza Lienlaf, Fumiaki Hayashi, Francesca Di Nunzio, +4

Journal of Virology

Transcriptional RegulationViral ReplicationHiv-1 RestrictionE3-ubiquitin Ligase ActivityRing Domain +13

RING Domain Mutations Uncouple TRIM5α Restriction of HIV-1 from Inhibition of Reverse Transcription and Acceleration of Uncoating

Amanda Roa, Fumiaki Hayashi, Yang Yang, +8

Journal of Virology

Viral ReplicationNatural SciencesViral Polymerase MechanismGeneticsImmunology +13

Essential role for histone deacetylase 11 (HDAC11) in neutrophil biology

Eva Sahakian, Jie Chen, John J. Powers, +17

Journal of Leukocyte Biology