Jay V. Johnson

2,4-Diamino-5-benzylpyrimidines and analogs as antibacterial agents. 12. 1,2-Dihydroquinolylmethyl analogs with high activity and specificity for bacterial dihydrofolate reductase

Jay V. Johnson, Barbara S. Rauckman, David P. Baccanari et al. · Journal of Medicinal Chemistry · 1989 · 208 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

2,4-Diamino-5-benzylpyrimidines and analogs as antibacterial agents. 10. 2,4-Diamino-5-(6-quinolylmethyl)- and -[(tetrahydro-6-quinolyl)methyl]pyrimidine derivatives. Further specificity studies

Barbara S. Rauckman, Mary Y. Tidwell, Jay V. Johnson et al. · Journal of Medicinal Chemistry · 1989 · 58 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Benzoquinazoline inhibitors of thymidylate synthase: enzyme inhibitory activity and cytotoxicity of some 3-amino- and 3-methylbenzo[f]quinazolin-1(2H)-ones

William Pendergast, Jay V. Johnson, Scott H. Dickerson et al. · Journal of Medicinal Chemistry · 1993 · 55 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8

Benzoquinazoline inhibitors of thymidylate synthase: enzyme inhibitory activity and cytotoxicity of some sulfonamidobenzoylglutamate and related derivatives

William Pendergast, Scott H. Dickerson, Jay V. Johnson et al. · Journal of Medicinal Chemistry · 1993 · 14 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14