Samantha M. Sarett

Lipophilic siRNA targets albumin in situ and promotes bioavailability, tumor penetration, and carrier-free gene silencing

Samantha M. Sarett, Thomas A. Werfel, Linus Lee et al. · Proceedings of the National Academy of Sciences · 2017 · 130 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17

Zwitterionic Nanocarrier Surface Chemistry Improves siRNA Tumor Delivery and Silencing Activity Relative to Polyethylene Glycol

Meredith A. Jackson, Thomas A. Werfel, Elizabeth J. Curvino et al. · ACS Nano · 2017 · 126 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17

Local Delivery of PHD2 siRNA from ROS‐Degradable Scaffolds to Promote Diabetic Wound Healing

John R. Martin, Christopher E. Nelson, Mukesh Kumar Gupta et al. · Advanced Healthcare Materials · 2016 · 89 citations · Full text

Engineering, Bioengineering, Biomedical Engineering +17

Selective mTORC2 Inhibitor Therapeutically Blocks Breast Cancer Cell Growth and Survival

Thomas A. Werfel, Shan Wang, Meredith A. Jackson et al. · Cancer Research · 2018 · 82 citations

Medicine, Oncology, Pharmacology +17

Hydrophobic interactions between polymeric carrier and palmitic acid-conjugated siRNA improve PEGylated polyplex stability and enhance in vivo pharmacokinetics and tumor gene silencing

Samantha M. Sarett, Thomas A. Werfel, Irene Chandra et al. · Biomaterials · 2016 · 48 citations

Pharmacy, Molecular Pharmaceutics, Oncology +17